PKA alpha/beta CAT (Phospho-Thr197) Antibody MBS9408988 from MyBioSource.com

Description

Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts

Product Specs
ItemPKA alpha/beta CAT (Phospho-Thr197) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS9408988
Quantity0.05 ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
PurityAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
ReactivityHuman, Mouse
TargetPKA alpha/beta CAT
Molecular Weight39,822 Da
HostRabbit
ImmunogenThe antibody detects endogenous levels of PKA a/b CAT only when phosphorylated at threonine 197
NCBI Full Gene Nameprotein kinase, cAMP-dependent, catalytic, alpha
NCBI Gene AliasesPKACA, PPNAD4
ClonalityPolyclonal